Blood Conservation and Management
General | Blood substitutes | News | Papers | Associations & Organizations
General
- Arinsburg SA, Skerrett DL, Karp JK, Ness PM, Jhang J, Padmanabhan A, Gibble J, Schwartz J, King KE, Cushing MM. Conversion to low transfusion-related acute lung injury (TRALI)-risk plasma significantly reduces TRALI. (April 2012)
- Sørensen B, Larsen OH, Rea CJ, Tang M, Foley JH, Fenger-Eriksen C. Fibrinogen as a hemostatic agent. Semin Thromb Hemost. (April 2012)
- Lucas CE, Ledgerwood AM. Fresh frozen plasma/red blood cell resuscitation regimen that restores procoagulants without causing adult respiratory distress syndrome. J Trauma Acute Care Surg. (April 2012)
- Neal MD, Hoffman MK, Cuschieri J, Minei JP, Maier RV, Harbrecht BG, Billiar TR, Peitzman AB, Moore EE, Cohen MJ, Sperry JL. Crystalloid to packed red blood cell transfusion ratio in the massively transfused patient: When a little goes a long way. J Trauma Acute Care Surg. (April 2012)
- Silva Junior JM, Rezende E, Amendola CP, Tomita R, Torres D, Ferrari MT, Toledo DO, Oliveira AM, Marques JA. Red blood cell transfusions worsen the outcomes even in critically ill patients undergoing a restrictive transfusion strategy. Sao Paulo Med J. (2012)
- Blood CME Center Fibrinogen and Perioperative Bleeding in Cardiac Surgery
- Red Blood Cell Transfusion: A Clinical Practice Guideline From the AABB (26 March 2012)
- Carson J, et al (the FOCUS investigators). Restrictive blood transfusion was fine for high-CV-risk patients after hip fracture repair (RCT, NEJM). N Engl J Med ePub December 14, 2011.
- Do Cardiac Surgery Patients Need So Many Blood Transfusions? (15 November 2010)
- Transfusion-Alternative Strategies Video Presentation - available at Perfusion.com (7 November 2010)
- New guidance for emergency blood provision Nursingtimes.net (12 November 2010)
- Transfusion Rates Vary Extremely in Cardiac Bypass Surgery DukeHealth.org (12 October 2010)
- Heart Surgery Patients Do Fine With Fewer Blood Transfusions: Study U.S.News & World Report (12 October 2010)
- Blood transfusions overused in cardiac surgery theHeart.org (12 October 2010)
- The truth about transfusions PBS Video. (16 August 2010)
- Evidence in favor of bloodless surgery mounts
- Blood products should be used conservatively in heart-surgery patients, trial shows (28 Oct. 2009)
- 10 Facts About Blood Transfusions That Every Physician, Nurse, Perfusionist & Hospital Executive Should Know
- Blood transfusion and outcomes - International panel of experts finds little evidence for transfusions improving health (23 April 2009)
- Soon, all eyes on better blood use (CAP Today, Dec. 2008)
- Anemia and surgery: From the preoperative period to postoperative recovery (National Anemia Action Council , 3 Dec. 2008)
- Bloodless surgery clears way for better care (14 July 2008)
- Fewer transfusions lowers costs, helps patient (5 May 2008)
- TrasylolR in the news
- Lawsuit filed against Bayer over Trasylol risks (7 Dec. 2008)
- Researcher estimates 22,000 lives could have been saved had Trasylol been pulled earlier (CBS 60 minutes, Feb. 17, 2008)
- Bayer pulls heart surgery drug Trasylol (6 Nov. 2007)
- Bayer temporarily suspends global Trasylol® marketing (5 Nov. 2007)
Blood myths (NSW Govt., Australia)
- Myth 1: "Blood, it's safer than it's ever been"
- Myth 2: "A blood transfusion will get my patient home sooner"
- Myth 3: "Blood transfusions improve healing"
- Myth 4: "Autologous blood (pre-donated) is risk-free"
- Myth 5: "Blood, it's free anyway"
Blood Substitutes
Blood Management
- Joint Commission: Blood Management Performance Measures Project
Tonelli M, Hemmelgarn B, Reiman T, Manns B, Reaume MN, Lloyd A, Wiebe N, Klarenbach S. Benefits and harms of erythropoiesis-stimulating agents for anemia related to cancer: a meta-analysis. CMAJ 2009 Apr 30; [Epub ahead of print]- Bohlius J, et al. Recombinant human erythropoiesis-stimulating agents and mortality in patients with cancer: a meta-analysis of randomised trials. The Lancet 2009 May2; 373(9674): 1532–42.
- NATA: Transfusion Alternatives in Transfusion Medicine: TOC - Current journal
- Safety and Effectiveness of Two Blood Transfusion Strategies in Surgical Patients With Cardiovascular Disease (FOCUS) (clinicaltrials.gov)
- AABB, ARC, ABC: Joint Statement Before the Advisory Committee on Blood Safety and Availability, May 30, 2008: Clinical Significance of Red Cell Age in Transfusions
- Older Red Cells - BEST Collaborative view of the evidence (presentation to U.S. Dept of HHS Advisory Committee on Blood Safety & Availability, 30 May 2008 - 55 slides)
- Isbister J. From transfusion to patient blood management (72-slide presentation)
- Treating patients like Jehovah's Witnesses could save lives: experts say (28 May 2007)
- Taking a harder line on blood transfusions (CAP Today, May 2007)
- FDA strengthens safety information for erythropoiesis-stimulating agents (9 Mar. 2007)
- Important warning: erythropoiesis-stimulating agents (12 Mar. 2007)
- Predictor of mortality In cardiac patients found by researchers
- Blood transfusions should be used in moderation for acute coronary syndrome (Duke University study)
- Doctors question whether all blood transfusions are effective and necessary. Br Med J 2005 Mar12;330:558.
- SABM Reference Library
- Transfusion Alert: Use of Autologous Blood (National Heart, Lung, and Blood Institute)
- Transfusion brings experts' blood to a boil (The Australian, 16 June 2007)
- US heart patients receive more transfusions than international patients (Medical News Today, 18 Nov. 2005)
Blood Management Papers
- Anemia Management and Blood Conservation in the Hospital Setting (CME/CE)
- Alghamdi AA, Albanna MJ, Guru V, Brister SJ. Does the use of erythropoietin reduce the risk of exposure to allogeneic blood transfusion in cardiac surgery? A systematic review and meta-analysis. J Card Surg 2006 May-Jun;21(3):320-6.
- Barone J, et al. Blood doping in the surgical intensive care unit: evidence-based surgical rebuttal. Surgery. 2007 Jan;141(1):7-8
- Beckmann SR, Carlile D, Bissinger RC, Burrell M, Winkler T, Shely WW. Improved coagulation and blood conservation in the golden hours after cardiopulmonary bypass. J Extra Corpor Technol 2007 Jun;39(2):103-8.
- Bennett J, Haynes S, Torella F, Grainger H, McCollum C. Acute normovolemic hemodilution in moderate blood loss surgery: a randomized controlled trial. Transfusion 2006 Jul;46(7):1097-103.
- Bennett-Guerrero E, Zhao Y, O'Brien SM, Ferguson TB Jr, Peterson ED, Gammie JS, Song HK. Variation in Use of Blood Transfusion in Coronary Artery Bypass Graft Surgery.JAMA 2010;304(14):1568-1575.
- Brandt MM, Rubinfeld I, Jordan J, Trivedi D, Horst HM. Transfusion insurgency: practice change through education and evidence-based recommendations. Am J Surg 2009 Mar;197(3):279-83.
- Bursi F, Barbieri A, Politi L, Di Girolamo A, Malagoli A, Grimaldi T, et al. Perioperative red blood cell transfusion and outcome in stable patients after elective major vascular surgery. Eur J Vasc Endovasc Surg 2008 Dec 24. [Epub ahead of print]
- Cardone D, Klein AA. Perioperative blood conservation. Eur J Anaesthesiol. 2009 May 14.
- Carless P, Henry D, Moxey A, O'connell D, Brown T, Fergusson D. Cell salvage for minimising perioperative allogeneic blood transfusion. Cochrane Database Syst Rev. 2006 Oct 18;4:CD001888.
- Ciurea SO, Hoffman R. Cytokines for the treatment of thrombocytopenia. Semin Hematol 2007 Jul; 44(3):166-82.
- Donat R Spahn DR, Marcucci C. Blood management in intensive care medicine: CRIT and ABC – what can we learn? Crit Care. 2004; 8(2): 89–90.
- Ela Y, Emmiler M, Kocogullari CU, Terzi Y, Sivaci RG, Cekirdekci A. Advantages of autologous blood transfusion in off-pump coronary artery bypass. Heart Surgery Forum 2009 Oct;12(5): E261 - E265.
- Feltracco P, Michieletto E, Barbieri S, Serra E, Rizzi S, Salvaterra F, Cillo U, Ori C. Microbiologic contamination of intraoperative blood salvaged during liver transplantation. Transplant Proc. 2007 Jul-Aug;39(6):1889-91.
- Fergusson DA, McIntyre L. The future of clinical trials evaluating blood substitutes. JAMA 2008 May 21;299(19):2324-6. Epub 2008 Apr 28.
- Fliser D, Haller H. Erythropoietin and treatment of non-anemic conditions-cardiovascular protection. Semin Hematol 2007 Jul;44(3):212-7.
- Freedman J, Luke K, Monga N, Lincoln S, Koen R, Escobar M, Chiavetta J. A provincial program of blood conservation: The Ontario Transfusion Coordinators (ONTraC). Transfus Apher Sci 2005 Nov;33(3):343-9.
- Gerber DR. Transfusion of packed red blood cells in patients with ischemic heart disease. Crit Care Med. 2008 Apr;36(4):1068-74
- Gould S, Cimino MJ, Gerber DR. Packed red blood cell transfusion in the intensive care unit: limitations and consequences. Am J Crit Care. 2007 Jan;16(1):39-48.
- Hajjar LA, Vincent JL, Galas FR, Nakamura RE, Silva CM, Santos MH, et al.Transfusion requirements after cardiac surgery: the TRACS randomized controlled trial JAMA 2010;304(14):1559-67.
- Karger R, Kretschmer V. Modern concepts of autologous haemotherapy. Transfus Apheresis Sci 2005 Apr;32(2):185-96.
- Klein AA, Nashef SA, Sharples L, Bottrill F, Dyer M, Armstrong J, Vuylsteke A. A randomized controlled trial of cell salvage in routine cardiac surgery. Anesth Analg 2008 Nov;107(5):1487-95.
- Kristeller JL, Stahl RF, Roslund BP, Roke-Thomas M. Aprotinin use in cardiac surgery patients at low risk for requiring blood transfusion. Pharmacotherapy. 2007 Jul;27(7):988-94.
- Lee LY, DeBois WJ, Krieger KH, Isom OW. Transfusion therapy and blood conservation. In: Cohn LH, Edmunds LH Jr, eds. Cardiac surgery in the adult. New York: McGraw-Hill, 2003:389-400. (Table of Contents)
- Maglish Ehrman BL, Moore HA. Blood conservation strategies in cardiovascular surgery. Dimens Crit Care Nurs 2004 Nov/Dec; 23(6): 244-52.
- Moonen AF, Knoors NT, van Os JJ, Verburg AD, Pilot P. Retransfusion of filtered shed blood in primary total hip and knee arthroplasty: a prospective randomized clinical trial.Transfusion 2007 Mar;47(3):379-84.
- Munoz M, Leal-Noval R, Garcia-Erce JA. Intravenous iron in cardiac surgery. Semin Hematol 2006 Oct;43(4 Suppl 6):S39-42.
- Raghavan M, Marik PE. Anemia, allogenic blood transfusion, and immunomodulation in the critically ill (review). Chest 2005 Jan; 127(1):295-307.
- Rawn J.The silent risks of blood transfusion. Curr Opin Anaesthesiol. 2008 Oct;21(5):664-8.
- Reddy SM, Talwar S, Velayoudam D, Gharde P, Mallick V, Jha RK, et al. Multi-modality blood conservation strategy in open-heart surgery: an audit. Interact Cardiovasc Thorac Surg 2009 Sep;9(3):480-2. Epub 2009 Jun 30.
- Rossaint R, Bouillon B, Cerny V, Coats TJ, Duranteau J, Fernández-Mondéjar E, et al. Management of bleeding following major trauma: an updated European guideline. Crit Care. 2010 Apr 6;14(2):R52
- Scott BH, Seifert FC, Grimson R. Blood transfusion is associated with increased resource utilisation, morbidity and mortality in cardiac surgery. Ann Card Anaesth. 2008 Jan-Jun;11(1):15-9.
- Shander A, Hofmann A, Ozawa S, Javidroozi M. The true cost of red blood cell transfusion in surgical patients. ASH Poster Board III 127 (8 Dec. 2008)
- Shander A, Goodnough LT. Objectives and limitations of bloodless medical care. Curr Opin Hematol 2006 Nov;13(6):462-70.
- Shander A, Moskowitz D, Rijhwani TS. The safety and efficacy of "bloodless" cardiac surgery. Semin Cardiothorac Vasc Anesth 2005 Mar;9(1):53-63.
- Shehata N, Wilson K, Mazer CD, Tomlinson G, Streiner D, Hebert P, Naglie G. The proportion of variation in perioperative transfusion decisions in Canada attributable to the hospital. Can J Anaesth. 2007 Nov;54(11):902-7.
- Shehata N, Naglie G, Alghamdi AA, Callum J, Mazer CD, Hebert P, Streiner D, Wilson K. Risk factors for red cell transfusion in adults undergoing coronary artery bypass surgery: a systematic review. Vox Sang 2007 Jul;93(1):1-11.
- Stowell CP. What happened to blood substitutes? Transfus Clin Biol 2005 Nov 30; [Epub ahead of print]
- Tinmouth AT, McIntyre LA, Fowler RA. Blood conservation strategies to reduce the need for red blood cell transfusion in critically ill patients. CMAJ 2008;178 49-57.
- Virmani S, Tempe DK, Pandey BC, Cheema AS, Datt V, Garg M, et al. Acute normovolemic hemodilution is not beneficial in patients undergoing primary elective valve surgery.Ann Card Anaesth 2010 Jan-Apr;13(1):34-8.
- Watson N, Taylor C. Allogeneic blood transfusion - the alternatives. Hospital Pharmacist 2000 May; 7(5): 118-123.
- Whitson BA, Huddleston SJ, Savik K, Shumway SJ. Bloodless cardiac surgery is associated with decreased morbidity and mortality. J Card Surg 2007 Sep-Oct;22(5):373-8.
- Wiedermann CJ. Hydroxyethyl starch--can the safety problems be ignored? Wien Klin Wochenschr. 2004 Sep 30;116(17-18):583-94
- Zhao L, Wang B, You G, Wang Z, Zhou H. Effects of different resuscitation fluids on the rheologic behavior of red blood cells, blood viscosity and plasma viscosity in experimental hemorrhagic shock. Resuscitation 2008 Dec 5.
- Zilberberg MD, Shorr AF. Effect of a restrictive transfusion strategy on transfusion-attributable severe acute complications and costs in the US ICUs: a model simulation. BMC Health Services Research 2007;7:138. (31 Aug. 2007)
- The cost of blood: multidisciplinary consensus conference for a standard methodology. Transfus Med Rev 2005 Jan; 19(1):66-78.
- Changes in blood supplies, regulations, and transfusion practice. Clinicians need to prepare for shortages now. (editorial) (Br Med J 2005 Feb 5;330:268-9)
Associations & Organizations
- Anemia Institute
- Blood Management & Conservation
- Bloodless Healthcare Development, Inc.
- Blood substitutes/oxygen carriers
- Clinical Clarité
- Jehovah's Witness position on blood transfusion
- Jehovah's Witness stance on blood transfusion (Wikipedia)
- NATA , the Network for Advancement of Transfusion Alternatives
- New Jersey Institute for Bloodless Medicine and Surgery
- NoBlood.Org
- SABM, the Society for the Advancement of Blood Management
- Yourblood-yourchoice.com