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Important Perfusionist Articles

In the News | Scientific Literature

In the news:

Red Blood Cell Transfusion: A Clinical Practice Guideline From the AABB
New Threats to the U.S. Blood Supply
Blood transfusion from another person doubles infection risk after CABG surgery. BMJ;339:b3147
Heart bypass surgery better than angioplasty for certain patients, Stanford study shows
Hlatky MA, et al. Coronary artery bypass surgery compared with percutaneous coronary interventions for multivessel disease: a collaborative analysis of individual patient data from ten randomised trials. Lancet
Blood storage impacts survival rate in cardiac surgery patients
Koch CG, et al. Duration of red-cell storage and complications after cardiac surgery. N Engl J Med;358(12):1229-39.
Adamson JW. New blood, old blood, or no blood (editorial). N Engl J Med;358:1229-39.
Dennis Quaid recounts twins' drug ordeal
China plant played role in Baxter heparin linked to 4 deaths
Stents in the news
Heart bypass better than stents, study says
CABG better than stents (MSNBC video)
Transfusion for anemia may contribute to early bypass mortality for women (Society of Thoracic Surgeons Meeting)
Blood protein offers clues to heart attack in seemingly healthy people
Drug-eluting and bare-metal stents equal In risk Of blood clots, heart attacks and death
FDA revises labeling for Trasylol (Aprotinin injection) to strengthen safety warnings and limit usage of drug to specific situations
U.S. strengthens warning for heart surgery drug
Riley JB, Samolyk KA, Lich BV, Moskowitz B, Shander A. Results from the Perfusion.com cardiac surgery hematocrit trend survey: observations and evidence-based recommendations

Recent Important Articles

Jeffrey L. Carson, MD; Brenda J. Grossman, et. al Red Blood Cell Transfusion: A Clinical Practice Guideline From the AABB. Ann Intern Med.
Kruer RM, Ensor CR. Colloids in the intensive care unit. Am J Health Syst Pharm.;69(19):1635-42.
Torina AG, Silveira-Filho LM, Vilarinho KA, Eghtesady P, Oliveira PP, Sposito AC, Petrucci O Use of modified ultrafiltration in adults undergoing coronary artery bypass grafting is associated with inflammatory modulation and less postoperative blood loss: a randomized and controlled study. J Thorac Cardiovasc Surg.;144(3):663-70.
Amy Corderoy. Surgeons asked to cut use of blood transfusions.
Carl-Johan Jakobsena, Pia Katarina Ryhammera, Mariann Tangb, Jan Jesper Andreasenc and Poul Erik Mortensen. Transfusion of blood during cardiac surgery is associated with higher long-term mortality in low-risk patients.
Pattakos G, Koch CG, Brizzio ME, Batizy LH, Sabik JF, Blackstone EH, Lauer MS. Outcome of patients who refuse transfusion after cardiac surgery: a natural experiment with severe blood conservation.
Denise Mann. No Health Risk When Jehovah's Witnesses Refuse Blood: Study.
Zalman S. Agus, Perelman School, Dorothy Caputo. Bloodless Heart Surgery Risk Overstated.
Pandey S, Vyas GN. Adverse effects of plasma transfusion.
Desborough M, Stanworth S. Plasma transfusion for bedside, radiologically guided, and operating room invasive procedures.
Wang D, Sun J, Solomon SB, Klein HG, Natanson C. Transfusion of older stored blood and risk of death: a meta-analysis.
Bhaskar B, Dulhunty J, Mullany DV, Fraser JF. Impact of blood product transfusion on short and long-term survival after cardiac surgery: more evidence.
Roth-Isigkeit A, Borstel TV, Seyfarth M, Schmucker P. Perioperative serum levels of tumour-necrosis-factor alpha (TNF-alpha), IL-1 beta, IL-6, IL-10 and soluble IL-2 receptor in patients undergoing cardiac surgery with cardiopulmonary bypass without and with correction for haemodilution.
Arinsburg SA, Skerrett DL, Karp JK, Ness PM, Jhang J, Padmanabhan A, Gibble J, Schwartz J, King KE, Cushing MM. Conversion to low transfusion-related acute lung injury (TRALI)-risk plasma significantly reduces TRALI.
Sørensen B, Larsen OH, Rea CJ, Tang M, Foley JH, Fenger-Eriksen C. Fibrinogen as a hemostatic agent. Semin Thromb Hemost.
Lucas CE, Ledgerwood AM. Fresh frozen plasma/red blood cell resuscitation regimen that restores procoagulants without causing adult respiratory distress syndrome. J Trauma Acute Care Surg.
Neal MD, Hoffman MK, Cuschieri J, Minei JP, Maier RV, Harbrecht BG, Billiar TR, Peitzman AB, Moore EE, Cohen MJ, Sperry JL. Crystalloid to packed red blood cell transfusion ratio in the massively transfused patient: When a little goes a long way. J Trauma Acute Care Surg.
Silva Junior JM, Rezende E, Amendola CP, Tomita R, Torres D, Ferrari MT, Toledo DO, Oliveira AM, Marques JA. Red blood cell transfusions worsen the outcomes even in critically ill patients undergoing a restrictive transfusion strategy. Sao Paulo Med J.
Carson J, et al (the FOCUS investigators). Restrictive blood transfusion was fine for high-CV-risk patients after hip fracture repair (RCT, NEJM). N Engl J Med ePub.
Campbell J, Holland C, Richens D, Skinner H. Impact of cell salvage during cardiac surgery on the thrombelastomeric coagulation profile: a pilot study. Perfusion.
Ferraris VA, Davenport DL, Saha SP, Austin PC, Zwischenberger JB. Surgical Outcomes and Transfusion of Minimal Amounts of Blood in the Operating Room. ARCH SURG/VOL 147 (NO. 1).[ PDF version]
B. Blasi, A. D’Alessandro, N. Ramundo, L. Zolla Red blood cell storage and cell morphology.
Rutger M, Barbara B, Mart J, Leo VdW, Johanna W, Martin S, Erik B, Ernest B, Johanna VdB Storage time of blood products and transfusion-related acute lung injury.
Corcoran T, Emma Joy Rhodes J, Clarke S, Myles PS, Ho KM. Perioperative fluid management strategies in major surgery: a stratified meta-analysis. Anesth Analg.;114(3):640-51. Epub.
Hofmann A, Farmer S, Shander A. Five drivers shifting the paradigm from product-focused transfusion practice to patient blood management. Oncologist.;16 Suppl 3:3-11.
Yang L, Stanworth S, Hopewell S, Doree C, Murphy M. Is fresh-frozen plasma clinically effective? An update of a systematic review of randomized controlled trials. Transfusion.
Solomon C, Schöchl H, Hanke A, Calatzis A, Hagl C, Tanaka K, Rahe-Meyer N. Haemostatic therapy in coronary artery bypass graft patients with decreased platelet function: Comparison of fibrinogen concentrate with allogeneic blood products. Scand J Clin Lab Invest.;72(2):121-8. Epub.
Lancé MD, Ninivaggi M, Schols SE, Feijge MA, Oehrl SK, Kuiper GJ, Nikiforou M, Marcus MA, Hamulyak K, van Pampus EC, Ten Cate H, Heemskerk JW. Perioperative dilutional coagulopathy treated with fresh frozen plasma and fibrinogen concentrate: a prospective randomized intervention trial. Vox Sang.

Scientific Literature

Apostolakis EE, Koletsis EN, Baikoussis NG, Siminelakis SN, Papadopoulos GS. Strategies to prevent intraoperative lung injury during cardiopulmonary bypass. J Cardiothorac Surg., 5(1):1.
Arnestad JP, Hyllner M, Bengtson JP, Tylman M, Mollnes TE, Bengtsson A. Removal of activated complement from shed blood: comparison of high- and low-dilutional haemofiltration. Acta Anaesthesiol Scand;42(7):811-5.
Aronson D, Dann EJ, Bonstein L, Blich M, Kapeliovich M, Beyar R, et al. Impact of red blood cell transfusion on clinical outcomes in patients with acute myocardial infarction. Am J Cardiol.;102(2):115-9.
Banbury MK, Brizzio ME, Rajeswaran J, Lytle BW, Blackstone EH. Transfusion increases the risk of postoperative infection after cardiovascular surgery. J Am Coll Surg; 202(1):131-8.
Barak M, Katz Y. Microbubbles: pathophysiology and clinical implications. Chest;128(4):2918-32.
Baric D, Biocina B, Unic D, Sutlic Z, Rudez I, Vrca VB, Brkic K, Ivkovic M. Topical use of antifibrinolytic agents reduces postoperative bleeding: a double-blind, prospective, randomized study. Eur J Cardiothorac Surg.; [Epub ahead of print]
Basran S, Frumento RJ, Cohen A, Lee S, Du Y, Nishanian E, et al. The association between duration of storage of transfused red blood cells and morbidity and mortality after reoperative cardiac surgery. Anesth Analg;103(1):15-20.
Belway D, Rubens FD, Wozny D, Henley B, Nathan HJ. Are we doing everything we can to conserve blood during bypass? A national survey. Perfusion; 20(5):237-41.
Beohar N, et al. Off-label DES use causing high complication rates. JAMA; 297(18).
Win HK, er al. Clinical outcomes and stent thrombosis following off-label use of drug-eluting stents. JAMA; 297(18).
Blijdorp K, Cransberg K, Wildschut ED, Gischler SJ, Jan Houmes R, Wolff ED, Tibboel D. Haemofiltration in newborns treated with extracorporeal membrane oxygenation: A case-comparison study. Crit Care; 13(2):R48. [Epub ahead of print]
Boodhwani M, Williams K, Babaev A, Gill G, Saleem N, Rubens FD. Ultrafiltration reduces blood transfusions following cardiac surgery: a meta-analysis. Eur J Cardiothorac Surg; [Epub ahead of print]
Bracey AW, Grigore AM, Nussmeier NA. Impact of platelet testing on presurgical screening and implications for cardiac and noncardiac surgical procedures. Am J Cardiol;98(10S1):S25-S32.
Bursi F, Barbieri A, Politi L, Di Girolamo A, Malagoli A, Grimaldi T, et al. Perioperative red blood cell transfusion and outcome in stable patients after elective major vascular surgery. Eur J Vasc Endovasc Surg. [Epub ahead of print]
Campbell JA, Holt DW, Shostrom VK, Durham SJ. Influence of intraoperative fluid volume on cardiopulmonary bypass hematocrit and blood transfusions in coronary artery bypass surgery. J Extra Corpor Technol;40(2):99-108.
Chandler WL. Effects of hemodilution, blood loss, and consumption on hemostatic factor levels during cardiopulmonary bypass. J Cardiothorac Vasc Anesth; 19(4):459-67.
Cina CS, Clase CM. Coagulation disorders and blood product use in patients undergoing thoracoabdominal aortic aneurysm repair. Transfus Med Rev; 19(2):143-54.
Cotton BA, Guy JS, Morris JA Jr, Abumrad NN. The cellular, metabolic, and systemic consequences of aggressive fluid resuscitation strategies. Shock; 26(2):115-21.
Eising GP, Niemeyer M, Günther T, Tassani P, Pfauder M, Schad H, Lange R. Does a hyperoncotic cardiopulmonary bypass prime affect extravascular lung water and cardiopulmonary function in patients undergoing coronary artery bypass surgery? Eur J Cardiothorac Surg; 20(2):282-9.
Eising GP, Pfauder M, Niemeyer M, Tassani P, Schad H, Bauernschmitt R, et al. Retrograde autologous priming: is it useful in elective on-pump coronary artery bypass surgery?Ann Thorac Surg; 75(1):23-7.
Engoren M, Habib RH, Hadaway J, Zacharias A, Schwann TA, Riordan CJ, et al. The effect on long-term survival of erythrocyte transfusion given for cardiac valve operations. Ann Thorac Surg; 88(1):95-100, 100.e1-3.
Feltracco P, Michieletto E, Barbieri S, Serra E, Rizzi S, Salvaterra F, Cillo U, Ori C. Microbiologic contamination of intraoperative blood salvaged during liver transplantation. Transplant Proc.; 39(6):1889-91.
Gerber DR. Transfusion of packed red blood cells in patients with ischemic heart disease. Crit Care Med.; 36(4):1068-74.
Glance LG, Dick AW, Mukamel DB, Fleming FJ, Zollo RA, Wissler R, et al. Association between Intraoperative Blood Transfusion and Mortality and Morbidity in Patients Undergoing Noncardiac Surgery. Anesthesiology; 114(2):283-29.
Goodnough LT, Shander A, Spivak JL, Waters JH, Friedman AJ, Carson JL, et al. Detection, evaluation, and management of anemia in the elective surgical patient. Anesth Analg; 101(6):1858-61.
Guo XY, Duan H, Wang JJ, Luo AL, Ye TH, Huang YG, et al. Effect of intraoperative using cell saver on blood sparing and its impact on coagulation function [Chinese]. Zhongguo Yi Xue Ke Xue Yuan Xue Bao; 26(2):188-91.
Groeneveld ABJ, Evert K. Jansen EK, Verheij J. Mechanisms of pulmonary dysfunction after on-pump and off-pump cardiac surgery: a prospective cohort study. J Cardiothoracic Surg; 2:11.
Gu YJ, Vermeijden WJ, de Vries AJ, Hagenaars JA, Graaff R, van Oeveren W. Influence of mechanical cell salvage on red blood cell aggregation, deformability, and 2, 3-diphosphoglycerate in patients undergoing cardiac surgery with cardiopulmonary bypass. Ann Thorac Surg; 86(5):1570-5.
Guyton RA. Coronary artery bypass is superior to drug-eluting stents in multivessel coronary artery disease. Ann Thorac Surg; 81(6):1949-57.
Habib RH, Zacharias A, Schwann TA, Riordan CJ, Engoren M, Durham et al. Role of hemodilutional anemia and transfusion during cardiopulmonary bypass in renal injury after coronary revascularization: implications on operative outcome. Crit Care Med.; 33(8):1749-56.
Hannan EL, Racz MJ, Walford G, Jones RH, Ryan TJ, Bennett E, et al. Long-term outcomes of coronary-artery bypass grafting versus stent implantation. N Engl J Med; 352(21):2174-83.
Huang H, Yao T, Wang W, Zhu D, Zhang W, Chen H, Fu W. Continuous ultrafiltration attenuates the pulmonary injury that follows open heart surgery with cardiopulmonary bypass. Ann Thorac Surg.; 76(1):136-40.
Jacob M, Chappell D, Hollmann MW. Current aspects of perioperative fluid handling in vascular surgery. Curr Opin Anaesthesiol.; 22(1):100-8.
Jani SM, Smith DE, Share D, Kline-Rogers E, Khanal S, O'Donnell MJ, Gardin J, Moscucci M. Blood transfusion and in-hospital outcomes in anemic patients with myocardial infarction undergoing percutaneous coronary intervention. Clin Cardiol; 30(10 Suppl 2):II49-56.
Jones TJ, Deal DD, Vernon JC, Blackburn N, Stump DA. How effective are cardiopulmonary bypass circuits at removing gaseous microemboli? J Extra Corpor Technol; 34(1):34-9.
Kamijo Y, Soma K, Sugimoto K, Tsuruta H, Ohwada T. The effect of a hemofilter during extracorporeal circulation on hemodynamics in patients with SIRS. Intensive Care Med; 26(9):1355-9.
Karkouti K, Wijeysundera DN, Beattie WS; Reducing Bleeding in Cardiac Surgery (RBC) Investigators. Risk associated with preoperative anemia in cardiac surgery: a multicenter cohort study. Circulation. 2008 Jan 29;117(4):478-84. Epub.
Karkouti K, Djaiani G, Borger MA, Beattie WS, Fedorko L, Wijeysundera D, et al. Low hematocrit during cardiopulmonary bypass is associated with increased risk of perioperative stroke in cardiac surgery. Ann Thorac Surg; 80(4):1381-7.
Kestin AS, Valeri CR, Khuri SF, Loscalzo J, Ellis PA, MacGregor H, et al. The platelet function defect of cardiopulmonary bypass. Blood; 82(1):107-17. [Medline abstract]
Khuri SF, Valeri CR, Loscalzo J, Weinstein MJ, Birjiniuk V, Healey NA, et al. Heparin causes platelet dysfunction and induces fibrinolysis before cardiopulmonary bypass. Ann Thorac Surg;60(4):1008-14.
Kleisli T, Cheng W, Jacobs MJ, Mirocha J, Derobertis MA, Kass RM, et al. In the current era, complete revascularization improves survival after coronary artery bypass surgery. J Thorac Cardiovasc Surg; 129(6):1283-91.
Restoring flow to all blocked areas of the heart improves 5-Year survival rate (Newswise)
Koch C, Li L, Figueroa P, Mihaljevic T, Svensson L, Blackstone EH. Transfusion and pulmonary morbidity after cardiac surgery. Ann Thorac Surg.; 88(5):1410-8.
Koch CG, Khandwala F, Li L, Estafanous FG, Loop FD, Blackstone EH. Persistent effect of red cell transfusion on health-related quality of life after cardiac surgery. Ann Thorac Surg; 82(1):13-20.
Koster A, Chew D, Merkle F, Gruendel M, Jurmann M, Kuppe H, Oertel R. Extracorporeal elimination of large concentrations of tirofiban by zero-balanced ultrafiltration during cardiopulmonary bypass: an in vitro investigation. Anesth Analg; 99(4):989-92.
Kuduvalli M, Oo AY, Newall N, Grayson AD, Jackson M, Desmond MJ, Fabri BM, Rashid A. Effect of peri-operative red blood cell transfusion on 30-day and 1-year mortality following coronary artery bypass surgery. Eur J Cardiothorac Surg; 27(4):592-8.
Kuduvalli M, Newall N, Stott A, Grayson AD, Fabri BM. Impact of avoiding cardiopulmonary bypass for coronary surgery on perioperative cardiac enzyme release and survival.Eur J Cardiothorac Surg; [Epub ahead of print]
Kurusz M, Butler BD. Bubbles and bypass: an update. Perfusion; 19 (Suppl 1):S49-S55.
Lee LY, DeBois WJ, Krieger KH, Isom OW. Transfusion therapy and blood conservation. In: Cohn LH, Edmunds LH Jr, eds. Cardiac surgery in the adult. New York: McGraw-Hill, 389-400. (Table of Contents)
Lee LY, DeBois W, Krieger KH, Girardi LN, Russo L, McVey J, et al. The effects of platelet inhibitors on blood use in cardiac surgery (review). Perfusion; 17(1):33-7
Legare JF, Hirsch G. Off-pump coronary artery bypass graft surgery is standard of care: Where do you stand? Can J Cardiol; 22(13):1107-10.
Legare JF, Buth KJ, Hirsch GM. Conversion to on pump from OPCAB is associated with increased mortality: results from a randomized controlled trial. Eur J Cardiothorac Surg; 27(2):296-301.
Levy JH, Tanaka KA, Steiner ME. Evaluation and management of bleeding during cardiac surgery. Curr Hematol Rep; 4(5):368-72.
Li T, Fang Y, Zhu Y, Fan X, Liao Z, Chen F, et al. A Small Dose of Arginine Vasopressin in Combination with Norepinephrine is a Good Early Treatment for Uncontrolled Hemorrhagic Shock After Hemostasis. J Surg Res.[Epub ahead of print]
Lilly KJ, O'Gara PJ, Treanor PR, Reardon D, Crowley R, Hunter C, et al. Cardiopulmonary bypass: it's not the size, it's how you use it! Review of a comprehensive blood-conservation strategy. J Extra Corpor Technol; 36(3):263-8.
Loeffelbein F, Zirell U, Benk C, Schlensak C, Dittrich S. High colloid oncotic pressure priming of cardiopulmonary bypass in neonates and infants: implications on haemofiltration, weight gain and renal function. Eur J Cardiothorac Surg.; 34(3):648-52. Epub.
Mathew JP, Mackensen GB, Phillips-Bute B, Stafford-Smith M, Podgoreanu MV, Grocott HP, Hill SE, Smith PK, Blumenthal JA, Reves JG, Newman MF; Neurologic Outcome Research Group (NORG) of the Duke Heart Center. Effects of extreme hemodilution during cardiac surgery on cognitive function in the elderly. Anesthesiology; 107(4):577-84.
Martini J, Cabrales P, Tsai AG, Intaglietta M. Mechanotransduction and the homeostatic significance of maintaining blood viscosity in hypotension, hypertension and haemorrhage. J Intern Med; 259(4):364-72.
Morgan TO. Cost, quality, and risk: Measuring and stopping the hidden costs of coronary artery bypass graft surgery. Am J Health Syst Pharm; 62(18_Supplement_4):S2-S5.
Munoz M, Ariza D, Gomez-Ramirez S, Henandez P, G arcia-Erce JA, Leal-Noval SR. Preoperative anemia in elective cardiac surgery: prevalence, risk factors, and influence on postoperative outcome.Transfusion Alternatives in Transfusion Medicine.; 11(2):47-56.
Murphy GJ. Does blood transfusion harm cardiac surgery patients? BMC Med.; 7:38.
Murphy GJ, Reeves BC, Rogers CA, Rizvi SI, Culliford L, Angelini GD. Increased mortality, postoperative morbidity, and cost after red blood cell transfusion in patients having cardiac surgery. Circulation.; [Epub ahead of print]
Murphy GS, Szokol JW, Nitsun M, Alspach DA, Avram MJ, Vender JS, et al. Retrograde autologous priming of the cardiopulmonary bypass circuit: safety and impact on postoperative outcomes. J Cardiothorac Vasc Anesth; 20(2):156-61. Epub.
Ngaage DL, Cowen ME, Griffin S, Guvendik L, Cale AR. Early neurological complications after coronary artery bypass grafting and valve surgery in octogenarians. Eur J Cardiothorac Surg. [Epub ahead of print]
Niemi TT, Suojaranta-Ylinen RT, Kukkonen SI, Kuitunen AH. Gelatin and hydroxyethyl starch, but not albumin, impair hemostasis after cardiac surgery. Anesth Analg; 102(4):998-1006.
Nikolsky E, Mehran R, Sadeghi HM, Grines CL, Cox DA, Garcia E, et al. Prognostic impact of blood transfusion after primary angioplasty for acute myocardial infarction: analysis from the CADILLAC (Controlled Abciximab and Device Investigation to Lower Late Angioplasty Complications) Trial. JACC Cardiovasc Interv.; 2(7):633-5.
Nollert G, Schwabenland I, Maktav D, Kur F, Christ F, Fraunberger P, et al. Miniaturized cardiopulmonary bypass in coronary artery bypass surgery: marginal impact on inflammation and coagulation but loss of safety margins. Ann Thorac Surg; 80(6):2326-32.
Chaney MA. Review of Miniaturized cardiopulmonary bypass in coronary artery bypass surgery: marginal impact on inflammation and coagulation but loss of safety margins.
Norman MJ, Sistino JJ, Acsell JR. The effectiveness of low-prime cardiopulmonary bypass circuits at removing gaseous emboli. J Extra Corpor Technol; 36(4):336-42.
Oliver E, Carrio ML, Rodríguez-Castro D, Javierre C, Farrero E, Torrado H, Castells E, Ventura JL. Relationships among haemoglobin level, packed red cell transfusion and clinical outcomes in patients after cardiac surgery. Intensive Care Med; 35(9):1548-55. Epub.
Paiva P, Ferreira E, Antunes M. Bloodless open heart surgery: simple and safe. Rev Port Cardiol; 24(5):647-54.
Parolari A, Camera M, Alamanni F, Naliato M, Polvani GL, Agrifoglio M, et al. Systemic inflammation after on-pump and off-pump coronary bypass surgery: a one-month follow-up. Ann Thorac Surg; 84(3):823-8.
Prondzinsky R, Knupfer A, Loppnow H, Redling F, Lehmann DW, Stabenow I, et al. Surgical trauma affects the proinflammatory status after cardiac surgery to a higher degree than cardiopulmonary bypass. J Thorac Cardiovasc Surg; 129(4):760-6.
Rajagopalan S, Mascha E, Na J, Sessler DI. The effects of mild perioperative hypothermia on blood loss and transfusion requirement. Anesthesiology; 108(1):71-77.
Ranucci M, Biagioli B, Scolletta S, Grillone G, Cazzaniga A, Cattabriga I, Isgro G, Giomarelli P. Lowest hematocrit on cardiopulmonary bypass impairs the outcome in coronary surgery: An Italian multicenter study from the National Cardioanesthesia Database. Tex Heart Inst J; 33(3):300-305.
Ranucci M, Romitti F, Isgro G, Cotza M, Brozzi S, Boncilli A, Ditta A. Oxygen delivery during cardiopulmonary bypass and acute renal failure after coronary operations. Ann Thorac Surg; 80(6):2213-20.
Rao SV. Implications of bleeding and blood transfusion in percutaneous coronary intervention. Rev Cardiovasc Med.; 8 Suppl 3:S18-26.
Rex S, Brose S, Metzelder S, de Rossi L, Schroth S, Autschbach R, Rossaint R, Buhre W. Normothermic beating heart surgery with assistance of miniaturized bypass systems: the effects on intraoperative hemodynamics and inflammatory response. Anesth Analg; 102(2):352-62.
Rinder CS, Smith MJ, Rinder HM, Cortright DN, Brodbeck RM, Krause JE, Smith BR. Leukocyte effects of C5a-receptor blockade during simulated extracorporeal circulation.Ann Thorac Surg; 83(1):146-52.
Rodriguez RA, Rubens F, Belway D, Nathan HJ. Residual air in the venous cannula increases cerebral embolization at the onset of cardiopulmonary bypass. Eur J Cardiothorac Surg; 29(2):175-80. Epub.
Rosengart TK, DeBois W, O'Hara M, Helm R, Gomez M, Lang SJ, et al. Retrograde autologous priming for cardiopulmonary bypass: a safe and effective means of decreasing hemodilution and transfusion requirements. J Thorac Cardiovasc Surg; 115(2):426-38; discussion 438-9.
Rodriguez RA, Williams KA, Babaev A, Rubens F, Nathan HJ. Effect of perfusionist technique on cerebral embolization during cardiopulmonary bypass. Perfusion; 20(1):3-10.
Rossaint R, Bouillon B, Cerny V, Coats TJ, Duranteau J, Fernández-Mondéjar E, et al. Management of bleeding following major trauma: an updated European guideline. Crit Care.; 14(2):R52
Rubens FD, Boodhwani M, Mesana T, Wozny D, Wells G, Nathan HJ; Cardiotomy Investigators. The cardiotomy trial: a randomized, double-blind study to assess the effect of processing of shed blood during cardiopulmonary bypass on transfusion and neurocognitive function. Circulation; 116(11 Suppl):I89-97.
Russell JA, Navickis RJ, Wilkes MM. Albumin versus crystalloid for pump priming in cardiac surgery: meta-analysis of controlled trials. J Cardiothorac Vasc Anesth;18(4):429-37.
Schroeder S, von Spiegel T, Stuber F, Hoeft A, Preusse CJ, Welz A, et al. Interleukin-6 enhancement after direct autologous retransfusion of shed thoracic blood does not influence haemodynamic stability following coronary artery bypass grafting. Thorac Cardiovasc Surg; 55(2):68-72.
Schroth M, Plank C, Meissner U, Eberle KP, Weyand M, Cesnjevar R, et al. Hypertonic-hyperoncotic solutions improve cardiac function in children after open-heart surgery.Pediatrics; 118(1):e76-e84. Epub.
Schöttler J, Lutter G, Böning A, Soltau D, Bein B, Caliebe D, et al. Is there really a clinical benefit of using minimized extracorporeal circulation for coronary artery bypass grafting? Thorac cardiovasc Surg; 56(2): 65-70.
Scott BH, Seifert FC, Grimson R. Blood transfusion is associated with increased resource utilisation, morbidity and mortality in cardiac surgery. Ann Card Anaesth.; 11(1):15-9.
Scott EM, Buckland R. A systematic review of intraoperative warming to prevent postoperative complications. AORN J.; 83(5):1090-104, 1107-13.
Selnes OA, Grega MA, Bailey MM, Pham LD, Zeger SL, Baumgartner WA, McKhann GM. Cognition 6 years after surgical or medical therapy for coronary artery disease. Ann Neurol; 63(5):581-590. [Epub ahead of print]
Selnes OA, Grega MA, Borowicz LM Jr, Barry S, Zeger S, Baumgartner WA, et al. Cognitive outcomes three years after coronary artery bypass surgery: a comparison of on-pump coronary artery bypass graft surgery and nonsurgical controls. Ann Thorac Surg; 79(4):1201-9.
Shaffer KE, Pearman DT, Galen RS, Carville DG. A rapid platelet function assay used to regulate platelet transfusion prophylaxis following cardiopulmonary bypass surgery. J Extra Corpor Technol; 36(2):145-8.
Shapira OM, Aldea GS, Treanor PR, Chartrand RM, DeAndrade KM, Lazar HL, Shemin RJ. Reduction of allogeneic blood transfusions after open heart operations by lowering cardiopulmonary bypass prime volume. Ann Thorac Surg; 66(3):987-8.
Shehata N, Wilson K, Mazer CD, Tomlinson G, Streiner D, Hebert P, Naglie G. The proportion of variation in perioperative transfusion decisions in Canada attributable to the hospital. Can J Anaesth.; 54(11):902-7.
Shroyer AL, Grover FL, Hattler B, Collins JF, McDonald GO, Kozora E, Lucke JC, Baltz JH, Novitzky D; the Veterans Affairs Randomized On/Off Bypass (ROOBY) Study Group.On-pump versus off-pump coronary-artery bypass surgery. N Engl J Med; 361(19):1827-1837.
Silva JM Jr, Toledo DO, Magalhãs DD, Pinto MA, Gulinelli A, Sousa JM, et al. Influence of tissue perfusion on the outcome of surgical patients who need blood transfusion. J Crit Care. [Epub ahead of print]
Sirvinskas E, Veikutiene A, Benetis R, Grybauskas P, Andrejaitiene J, Veikutis V, Surkus J. Influence of early re-infusion of autologous shed mediastinal blood on clinical outcome after cardiac surgery. Perfusion.; 22(5):345-52.
Slight RD, Demosthenous N, Nzewi OC, Soliman AR, McClelland DB, Mankad PS. The effect of gain in total body water on haemoglobin concentration and body weight following cardiac surgery. Heart Lung Circ.; 15(4):256-60.
Slight RD, Demosthenous N, Nzewi OC, Soliman AR, McClelland DB, Mankad PS. The effect of gain in total body water on haemoglobin concentration and body weight following cardiac surgery. Heart Lung Circ; [Epub ahead of print]
Slight RD, Bappu NJ, Nzewi OC, McClelland DB, Mankad PS. Perioperative red cell, plasma, and blood volume change in patients undergoing cardiac surgery. Transfusion; 46(3):392-7.
Snyder-Ramos SA, Möhnle P, Weng YS, Böttiger BW, Kulier A, Levin J, Mangano DT; Investigators of the Multicenter Study of Perioperative Ischemia; MCSPI Research Group.The ongoing variability in blood transfusion practices in cardiac surgery. Transfusion [Epub ahead of print]
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